Handbook of Drugs in Intensive Care: An A-Z Guide (5th Edition)

Henry Paw, Rob Shulman, "Handbook of Drugs in Intensive Care: An A-Z Guide (5th Edition)"


2014 | ISBN-10: 1107484030 | 355 pages | PDF | 3 MB

A thoroughly updated edition of this well-established guide to drugs and prescribing for intensive care. The book is split into two sections: an A-Z guide to the drugs available, and concise notes on the key topics and situations faced on a daily basis. The A-Z section provides succinct information on each drug including uses, limitations, administration directions and adverse effects. The second section details complications that may arise in patients with particular conditions such as diabetes, epilepsy and renal failure, and other factors that may affect drug prescribing. This revised edition includes eleven new drug monographs and covers several new topics, including sepsis and drugs for organ donation. Inside the back cover is a colour fold-out chart showing drug compatibility for intravenous administration. Presented in a concise, compact format, this book is an invaluable resource for doctors, nurses, pharmacists and other healthcare professionals caring for critically ill patients.

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Photostability of Drugs and Drug Formulations, Second Edition

Hanne Hjorth Tonnesen, "Photostability of Drugs and Drug Formulations, Second Edition"


2004 | ISBN-10: 0415303230 | 448 pages | PDF | 8 MB

Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource.




The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results.




Features


Assists non-experts in this field design a test protocol and interpret the results


Covers in vitro and in vivo aspects of interactions between drugs and light


Explores the kinetic and chemical aspects of drug photodecomposition


Discusses the problems frequently encountered in photochemical stability testing


Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs


Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint


Offers specific guidance in photostability testing and screening of drug photoreactivity

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