Drug Trafficking, Organized Crime, and Violence in the Americas Today

Bruce M. Bagley and Jonathan D. Rosen, "Drug Trafficking, Organized Crime, and Violence in the Americas Today"


2015 | ISBN-10: 0813060680 | 472 pages | PDF | 2 MB

In 1971, Richard Nixon declared a war on drugs. Despite foreign policy efforts and attempts to combat supply lines, the United States has been for decades, and remains today, the largest single consumer market for illicit drugs on the planet. In this volume, Bruce Bagley and Jonathan Rosen illustrate that the war on drugs has been ineffective at best and, at worst, has been highly detrimental to countries throughout the region. They present a clear picture of drug trafficking and its role in organized crime while discussing the major trends of the war on drugs in the twentyfirst century, as well as its future. With this comprehensive overview, Bagley and Rosen develop a framework for understanding the limits and liabilities in the U.S.-championed war on drugs throughout the Americas.

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Photostability of Drugs and Drug Formulations, Second Edition

Hanne Hjorth Tonnesen, "Photostability of Drugs and Drug Formulations, Second Edition"


2004 | ISBN-10: 0415303230 | 448 pages | PDF | 8 MB

Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource.




The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results.




Features


Assists non-experts in this field design a test protocol and interpret the results


Covers in vitro and in vivo aspects of interactions between drugs and light


Explores the kinetic and chemical aspects of drug photodecomposition


Discusses the problems frequently encountered in photochemical stability testing


Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs


Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint


Offers specific guidance in photostability testing and screening of drug photoreactivity

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Adaptive Systems in Drug Design by Sung-Sau So

Adaptive Systems in Drug Design by Sung-Sau So


English | Jan. 2002 | ISBN: 158706118X, 1587060590 | 184 Pages | PDF | 2 MB

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.