Gene Therapy of Cochlear Deafness: Present Concepts and Future Aspects 1st Edition

Gene Therapy of Cochlear Deafness: Present Concepts and Future Aspects (Advances in Oto-Rhino-Laryngology, Vol. 66) by A.F. Ryan


English | May 26, 2009 | ISBN: 3805590350 | 127 Pages | PDF | 8 MB

Gene therapy holds great potential for the treatment not only of genetic disorders, but also of many acquired diseases. This is as true for the inner ear as for any other organ. However, the technical challenges that must be overcome before gene therapy becomes more widely used are remarkable. In the inner ear the size, accessibility, delicacy and the involvement of many different cell types present unique conditions. This volume reviews current concepts and recent research findings of the application of gene therapy to the inner ear. Various forms of gene therapy, disorders that are potential targets for gene therapy, techniques for gene delivery, and mechanisms of gene targeting, and also obstacles that have yet to be overcome are discussed. This volume will be indispensable reading for otolaryngologists, hearing scientists, audiologists with a special interest in keeping up-to-date on gene therapy for inner ear disorders.

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Postcolonialism and the Hebrew Bible: The Next Step

Postcolonialism and the Hebrew Bible: The Next Step by Roland Boer


English | 2013 | ISBN: 1589837711, 1589837703 | 290 pages | PDF | 4,6 MB

This volume returns to where initial interest in postcolonial biblical criticism began: the Hebrew Bible. It does so not to celebrate the significant achievements of postcolonial analysis over the last few decades but to ask what the next step might be. In these essays, established and newer scholars, many from the interstices of global scholarship, discuss specific texts, neo/post/colonial situations, and theoretical issues. Moving from the Caribbean to Greenland, from Ezra-Nehemiah to the Gibeonites, this collection seeks out new territory, new questions, and possibly some new answers. The contributors are Roland Boer, Steed Davidson, Richard Horsley, Uriah Y. Kim, Judith McKinlay, Johnny Miles, Althea Spencer-Miller, Leo Perdue, Christina Petterson, Joerg Rieger, and Gerald West.

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Adaptive Systems in Drug Design by Sung-Sau So

Adaptive Systems in Drug Design by Sung-Sau So


English | Jan. 2002 | ISBN: 158706118X, 1587060590 | 184 Pages | PDF | 2 MB

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.